argonaute rna

Argo Dual SiRNA

Lead Asset:

Bispecific validated in vivo

•  Safe and effective new drug for residual risk of cardiometabolic disease

•  Globally, 450 million live with ASCVD and each year 20 million die from ASCVD

•  Most are preventable

Clinical Entry Pathway

Rare orphan
Atherogenic Dyslipidaemias
Residual risk of Cardiometabolic disease

Mode of action

Bispecific siRNA enters the cell as a monomer, splitting into individual siRNAs in endosome, followed by target mRNA cleavage and reduction of target gene expression

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